How Preterm Labor Adjunctive Therapy HelpsNone Open Label Primary Purpose: Betamethasone Dosing Interval - 12 or 24 Hours? April Actual Primary Completion Date: October Actual Study Completion Date: The diagnosis of RDS is defined as:
Antenatal Corticosteroid Therapy for Fetal Maturation - ACOG
None Open Label Primary Purpose: Betamethasone Dosing Interval - 12 or 24 Hours? April Actual Primary Completion Date: October Actual Study Completion Date: The diagnosis of RDS is defined as: Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below.
For general information, Learn About Clinical Studies. Ages Eligible for Study: Female Accepts Healthy Volunteers: Yes Criteria Inclusion Criteria:. Hide glossary Glossary Study record managers: Search for terms x.
Warning You have reached the maximum number of saved studies The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U. Read our disclaimer for details. The purpose of this study is to determine if there may be a benefit to the newborn if betamethasone is given 12 hours apart instead of 24 hours apart.
Betamethasone is a medicine given to women expected to deliver after 24 but before 34 weeks of pregnancy. It is very advantageous in preventing or decreasing the many problems these small babies may face if born early. Betamethasone makes breathing easier for them, also decreases the chance of them bleeding in the head and makes their chances of survival better.
This medicine is used routinely in pregnancy but the best timing between doses in not well established. The 'standard' dosing schedule involves giving 2 injections of 12mg of the medicine 24 hours apart. However, many women deliver before reaching the hour mark, despite the doctors best efforts to try and delay delivery, and therefore miss the opportunity for the 2nd dose.
Genetic and Rare Diseases Information Center resources: Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Pregnant women expected to deliver preterm either induced or spontaneously for any obstetrical or medical indication. Gestational age between 23 and 34 weeks gestational age. Dating must either be by LMP which is consistent with ultrasound performed at any gestational age, or calculated by a sonogram less than or equal to 23 weeks.
Known drug allergy to betamethasone. Given steroid other than betamethasone for lung maturation. Any contraindication to steroid therapy. Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials. A controlled trial of antepartum glucocorticoid treatment for prevention of the respiratory distress syndrome in premature infants.
National Library of Medicine U. National Institutes of Health U. Department of Health and Human Services. March 28, Last Update Posted: Actual Primary Completion Date:. Actual Study Completion Date:. United States, New Jersey. Camden, New Jersey, United States, Atlanticare Regional Medical Center. The Cooper Health System.