DrostanoloneDrostanolone propionateor dromostanolone propionatesold under the brand names Drolban drostanolone propionate melting point, Masteriland Masteron among others, is an androgen and testosterone steroids types steroid AAS medication which was used to treat breast cancer in women but is now no longer marketed. Side effects of drostanolone propionate include symptoms of masculinization like acneincreased hair growthvoice changesand increased sexual desire. Drostanolone propionate was first described in and was introduced for medical use in dtostanolone The principal clinical indication of drostanolone propionate in the United States as well as international markets was the treatment of advanced inoperable breast cancer in women. Hormonal treatment is part of the complex therapy for some kind of tumors drostanolone propionate melting point, particularly the ones associated with hormone-active tissues like breast or prostate cancer.
Drostanolone propionate - Wikipedia
Drostanolone propionate , or dromostanolone propionate , sold under the brand names Drolban , Masteril , and Masteron among others, is an androgen and anabolic steroid AAS medication which was used to treat breast cancer in women but is now no longer marketed.
Side effects of drostanolone propionate include symptoms of masculinization like acne , increased hair growth , voice changes , and increased sexual desire. Drostanolone propionate was first described in and was introduced for medical use in The principal clinical indication of drostanolone propionate in the United States as well as international markets was the treatment of advanced inoperable breast cancer in women.
Hormonal treatment is part of the complex therapy for some kind of tumors , particularly the ones associated with hormone-active tissues like breast or prostate cancer. That is why drugs that block estrogen receptors or decrease their expression on the cell membrane, antiestrogens , could limit the tumor spread and size. Drostanolone propionate has been FDA approved  as an antiestrogenic drug for the treatment of breast cancer.
By the time of its release, there were not many alternatives for patients suffering from breast cancer and drostanolone propionate was a revolution for these patients. As it has lower androgenic rate compared to testosterone , the risk of virilization is much lighter. Due to this fact, women, who usually do not respond well to any AAS, were having much greater chance to survive cancer. Drostanolone propionate can also be used for breast tumors that do not respond well to other treatments or also as palliative care for advanced incurable tumors.
The effects of the product depend of course on the dose and period of administration. The risk of virilization becomes greater with high doses and continuous administration period. Drostanolone propionate is or has been used for physique- and performance-enhancing purposes by competitive athletes , bodybuilders , and powerlifters. Drostanolone propionate produces considerably less virilization in women compared to equal doses of testosterone propionate.
Drostanolone propionate is a prodrug of drostanolone. Drostanolone propionate, via its active form drostanolone, interacts with the AR and activates a cascade of genetic changes, including increased protein synthesis anabolism and decreased amino acid degradation catabolism. It also induces a reduction or inhibition of prolactin or estrogen receptors in the breasts , which is linked to its antitumor effects. Drostanolone propionate is not active via the oral route and must be administered via intramuscular injection.
Drostanolone and drostanolone propionate were first described in Drostanolone propionate was marketed under a variety of brand names including Drolban, Masterid, Masteril, Masteron, Masterone, Mastisol, Metormon, Permastril, and Prometholone.
Drostanolone propionate appears to no longer be marketed. From Wikipedia, the free encyclopedia. Journal of the American Chemical Society. Pharmaceutical Manufacturing Encyclopedia, 3rd Edition.
Drug Abuse Handbook, Second Edition. Elks 14 November The Dictionary of Drugs: Chemical Data, Structures and Bibliographies. Hall 6 December Concise Dictionary of Pharmacological Agents: Androstanolone stanolone, dihydrotestosterone, DHT Androstanolone esters Bolazine capronate Drostanolone propionate dromostanolone propionate Epitiostanol Mepitiostane Mesterolone Metenolone acetate methenolone acetate Metenolone enanthate methenolone enanthate Stenbolone acetate Nortestosterone derivatives: Bolandiol dipropionate Nandrolone esters e.