OxymetholoneExcipient information presented when oxymetolone limited, particularly for generics ; consult specific product labeling. Enhances production of erythropoietin in patients with oxymetholone para que serve which are due to bone marrow failure; stimulates erythropoiesis in anemias due to deficient red cell production. Treatment of anemias caused by deficient red cell production. Androgen therapy eg, oxymetholone is generally not appropriate for the treatment of anemias except in certain rare situations eg, Fanconi anemia. Data from a limited number of patients seve a oxymetholone para que serve tren steroid injection pain suggests that oxymetholone may be beneficial in the treatment of Fanconi anemia [Paustian ].
Oxymetholone (Professional Patient Advice) - cialispanettet.top
Excipient information presented when available limited, particularly for generics ; consult specific product labeling. Enhances production of erythropoietin in patients with anemias which are due to bone marrow failure; stimulates erythropoiesis in anemias due to deficient red cell production. Treatment of anemias caused by deficient red cell production.
Androgen therapy eg, oxymetholone is generally not appropriate for the treatment of anemias except in certain rare situations eg, Fanconi anemia.
Data from a limited number of patients in a retrospective review suggests that oxymetholone may be beneficial in the treatment of Fanconi anemia [Paustian ]. However, due to significant risks associated with therapy, a careful risk vs.
Additional data may be necessary to further define the role of oxymetholone in this condition. Hypersensitivity to oxymetholone or any component of the formulation; breast cancer in men; breast cancer in women with hypercalcemia; prostate cancer; severe hepatic dysfunction; nephrosis or nephrotic phase of nephritis; pregnancy or use in women who may become pregnant.
Fanconi anemia off-label use: Use with caution due to risk of edema in patients with renal impairment. Mild to moderate impairment: Specifically, the risk for cholestasis may be increased. Blood Glucose Lowering Agents: Androgens may enhance the hypoglycemic effect of Blood Glucose Lowering Agents. Androgens may enhance the thrombogenic effect of C1 inhibitors. May enhance the fluid-retaining effect of Androgens.
Vitamin K Antagonists eg, warfarin: Androgens may enhance the anticoagulant effect of Vitamin K Antagonists. Decreased thyroxine-binding globulin, T 4 ; increased resin uptake of T 3 and T 4. Acne vulgaris, androgenetic alopecia postpubertal males, females , hyperpigmentation. Benign prostatic hypertrophy elderly males , clitoromegaly, decreased ejaculate volume, epididymitis, erectile dysfunction increased erections; prepubertal males , impotence, irritable bladder, oligospermia, phallic enlargement, priapism, testicular atrophy, testicular disease, virilization females.
Cholestatic hepatitis, cholestatic jaundice, hepatic failure, hepatic necrosis, hepatocellular neoplasm including carcinoma , increased serum alkaline phosphatase, increased serum bilirubin, increased serum transaminases, peliosis hepatitis.
Increased creatine phosphokinase, premature epiphyseal closure children. Peliosis hepatis, a condition in which liver and, sometimes, splenic tissue is replaced with blood-filled cysts, has occurred in patients receiving androgenic anabolic steroids.
These cysts are sometimes present with minimal hepatic dysfunction and have been associated with liver failure. Often, they are not recognized until life-threatening liver failure or intra-abdominal hemorrhage develops. Withdrawal of drug usually results in complete disappearance of lesions.
Most often these tumors are benign and androgen-dependent, but fatal malignant tumors have occurred. Withdrawal of drug often results in regression or cessation of tumor progression. However, hepatic tumors associated with androgens or anabolic steroids are much more vascular than other hepatic tumors and may be silent until life-threatening, intra-abdominal hemorrhage develops.
Blood lipid changes associated with increased risk of atherosclerosis are seen in patients treated with androgens and anabolic steroids. The changes may be very marked and could have a serious impact on the risk of atherosclerosis and coronary artery disease.
Anabolic steroids may cause changes in blood lipids decreased high density lipoproteins and sometimes increased low density lipoproteins , increasing the risk of arteriosclerosis and coronary artery disease. Androgenic anabolic steroid treatment may cause peliosis hepatis, which occurs when splenic or hepatic tissue is replaced by cysts blood-filled ; may only cause minimal hepatic dysfunction although has been associated with hepatic failure.
Androgenic liver cell tumors, which may be benign, although malignant tumors have also been reported; generally regress when anabolic steroid treatment is withdrawn. Both conditions peliosis and tumors may not be apparent until liver failure or intra-abdominal hemorrhage develops. Androgen use low doses has also been associated with cholestatic hepatitis and jaundice; may be associated with hepatomegaly and right upper-quadrant pain; jaundice is typically reversible upon discontinuation continuing treatment has been associated with coma and death.
Monitor liver function periodically. Androgenic anabolic steroid use may cause prostatic hypertrophy or prostate cancer in elderly men. Use with caution in patients with diabetes mellitus; insulin or oral hypoglycemic needs may be altered; monitor carefully. Use with caution in patients with conditions influenced by edema eg, cardiovascular disease, migraine, seizure disorder, renal impairment ; may cause fluid retention.
May accelerate bone maturation without producing compensatory gain in linear growth in children; effect may continue for 6 months after treatment discontinuation; in prepubertal children perform radiographic examination of the hand and wrist every 6 months to determine the rate of bone maturation and to assess the effect of treatment on the epiphyseal centers.
Oxymetholone should not replace other anemia treatment supportive measures such as transfusion, correction of iron, folic acid, vitamin B 12 or pyridoxine deficiency, antibacterial therapy, and the appropriate use of corticosteroids. Periodic liver function tests, lipid profile, hemoglobin and hematocrit; iron studies; serum glucose may be decreased by testosterone, monitor patients with diabetes ; radiologic examination of bones every 6 months when using in prepubertal children ; monitor urine and serum calcium and signs of virilization in women treated for breast cancer.
Oligospermia or amenorrhea may occur resulting in an impairment of fertility. Use is contraindicated in women who are or may become pregnant. During this hospital stay, were you given any medicine that you had not taken before?
Before giving you any new medicine, how often did hospital staff tell you what the medicine was for? How often did hospital staff describe possible side effects in a way you could understand? Have patient report immediately to prescriber signs of liver problems dark urine, feeling tired, lack of appetite, nausea, abdominal pain, light-colored stools, vomiting, or yellow skin or eyes , priapism, acne, shortness of breath, excessive weight gain, swelling of arms or legs, urinary retention, change in amount of urine passed, muscle weakness, bruising, bleeding, severe anxiety, or signs of virilization in females a deep voice, facial hair, pimples, or period changes HCAHPS.
This is not a comprehensive list of all side effects. Patient should consult prescriber for additional questions. Intended Use and Disclaimer: Should not be printed and given to patients.
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