Pure and Organic CBD & and Hemp Products

Effective medicine provided by mother nature

  • Powerful relaxant

  • Strong painkiller

  • Stress reduction
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Why CBD?

More and more renowned scientists worldwide publish their researches on the favorable impact of CBD on the human body. Not only does this natural compound deal with physical symptoms, but also it helps with emotional disorders. Distinctly positive results with no side effects make CBD products nothing but a phenomenal success.

This organic product helps cope with:

  • Tight muscles
  • Joint pain
  • Stress and anxiety
  • Depression
  • Sleep disorder

Range of Products

We have created a range of products so you can pick the most convenient ones depending on your needs and likes.

CBD Capsules Morning/Day/Night:

CBD Capsules

These capsules increase the energy level as you fight stress and sleep disorder. Only 1-2 capsules every day with your supplements will help you address fatigue and anxiety and improve your overall state of health.

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CBD Tincture

CBD Tincture

No more muscle tension, joints inflammation and backache with this easy-to-use dropper. Combined with coconut oil, CBD Tincture purifies the body and relieves pain. And the bottle is of such a convenient size that you can always take it with you.

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Pure CBD Freeze

Pure CBD Freeze

Even the most excruciating pain can be dealt with the help of this effective natural CBD-freeze. Once applied on the skin, this product will localize the pain without ever getting into the bloodstream.

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Pure CBD Lotion

Pure CBD Lotion

This lotion offers you multiple advantages. First, it moisturizes the skin to make elastic. And second, it takes care of the inflammation and pain. Coconut oil and Shia butter is extremely beneficial for the health and beauty of your skin.

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What Are the Symptoms

content oil list simpson cbd rick

bildemon
15.05.2019

Content:

  • content oil list simpson cbd rick
  • FAQ about RSO
  • HEALTH A-Z & MARIJUANA NEWS
  • Cannabis oils may contain various concentrations of CBD, . The fact that the maximum CBD content in an oil is limited by the THC present in. Making Rick Simpson Oil simply and better, best strains to use, cancer research Purple Kush Indica strain- with a THC content of 22%. It routinely figures in 'top 10 most powerful strains in the world' lists, has a euphoric. WHAT DO I NEED TO PRODUCE RICK SIMPSON OIL? .. The only difference is , you will be using strains high in CBD content, instead of strains that contain a.

    content oil list simpson cbd rick

    Come to Santa Cruz, California where it is legal and readily available. If it saves your life the move is worth it. Only problem with the states that have legsl7zed just CBD is that the legal amount…here in Indiana I believe is 0. If medical marijuana was a cure all, big pharma would be marketing it.

    They have a huge advertising budget and would put small growers out of business. Mate I quit oxys, benzos, pregabalin and drinking due to cannabis. Fuck being addicted to the shit they were giving me and fuck these draconian laws.

    Well you must be in the pharma business since you know how much budget they have if medical marijuana,oil or other gives you even a little comfort to have a somewhat kinda normal day then I say Praise God…. Just posted my RSO Experience after surgery.

    I understand your concern. But properly extracted RSO should contain less than 0. But there may be something to the RSO process that creates a full-spectrum concentrate that is particularly effective in causing apoptosis the return to normal, programmed cell death which is the theory behind the use of cannabinoids in treating cancer.

    The ovarian cancer is the lb gorilla in the room with us. Started our grow so we can make rso. She has been trying different flowers and edibles and finding relief. I am sorry to hear about your diagnosis. I was also just diagnosed with the same. Stage IV and the cancer has also spread to my 2 hip sockets and my spine.

    I am very interested to know how this helped you as I see you wrote this 2 months ago. I am sorry to hear about what you are going through too… really anyone with this crap, my 81 year old father has it in his kidney and bladder and they say there is nothing they can do but surgery, he said nope.. I am too old for that.. Now do I know that to be fact? Am I willing to try anything to stay alive..

    I tried…but everyone is different. Get your card if your state has Medical Marijuana.. CBD by itself seems to be effective for certain symptoms anxiety, depression, chronic pain but not very effective for others acute pain, nausea, lack of appetite. Most need to literally start with a dose no larger than a single standard grain of rice. Then, over a period of a few weeks, you can slowly work your tolerance up to full dosage.

    He recommends 60 grams in as short a time period as practical generally 60 grams over about 90 days since the first month or so is spent in slowly building up tolerance. I personally can attest to taking about 80 grams over 45 days to treat my HIV and Chronic Hep B with excellent results.

    Meaning the synergistic effects of the combined cannabinoids and terpenoids in the plant are much greater than the effect of any single component including THC or CBD. Some CBD products as well only have a small amount of thc only to help it activate better u should try loon lion cbd for your parinoia. Not sure what State you are in.

    This is life or death folks. As for the actual efficacy of cannabinoids in the treatment of advanced cancer…this is groundbreaking. Supplemental antioxidants and other nutrients are probably critical to full effectiveness.

    As I am a terrible typist…please let me know if you want more info and we can chat directly. God Bless, Louis Byron. I agree with your whole statement except I do not think the cannibis works by destroying or interrupting the mitosis of cells as chemo and radiation Rx does but rather instead acts more as a supporter by perhaps reducing inflammation inside the body and supercharging the immune system.

    Broadly speaking, T-cells can be grouped into various subsets e. T helper type 1 Th1 cells are required for host defence against intracellular viral or bacterial pathogens and cancer. PMC , and both these can suppress antitumour immunity. It could also enhance tumorigenesis by interfering with tumour surveillance by the immune system PMID: A headline from Haaretz says medical marijuana can reduce effectiveness of immunotherapy cancer drug, Israeli research shows.

    The study was retrospective, observational and conducted by researchers in Israel who presented the findings at ESMO. They collected data from patients with advanced melanoma, non-small cell lung cancer NSCLC , and renal cell carcinoma RCC who were all treated with nivolumab.

    Eighty-nine received nivolumab alone, and 51 received both cannabis in combination with nivolumab. Among the melanoma and renal cancer patients, And one study is insufficient to provide reliable findings.

    They must be reproducible and replicated by other studies in order to develop credible conclusions. Vet cbd a product specifically made for pets it is cbd oil in a tincture u can drop into there food or directly in there mouth or water all to help for there pain and wellness.

    My wife and I make tea out of fan leaves off our plants, water it down a bit, and put it over our 12 year old huskies dry food. I surely hope you found a CBD oil for your kitty and yourself. I use CBD on all of my pets and the results are astounding! My viral loads are halving from applications but I know I can erradicate it and rebuild my immune system like you have done. Could we chat somehow? Louis…how might we chat more about RSO and your results privately?

    Stage 4b mastastic cervical cancer…looking for options where docs tell me I have none. I read where one of the components cbg I think actually was shown to kill cancer cells..?

    I see alot of comments in regards to this oil base helping with cancer or aids. If you can please respond i would appreciate it. I have colitis to… How did it help are you Still on meds?

    Did you make your rso? I live in Oregon and make my own RSO. Thanks for the quick reply. You use top quality indica buds to produce the oil in a rice cooker? What meds were you prior to taking rso. Different cannabinoids have different effects on various diseases, so we do a broad spectrum of cannabinoids to cover all the different diseases. Let me know if I can help you further after you watch the video.

    Sarah, I hope my reply is not too late. Intravenous Vit C is the best for peritonitis. I assume she is still in the hospital? Peritonitis is a serious condition. But only a few doctors use Vit C intravenously. If she is home, find a naturopathic doctor in your area and have high dose Vit C IV treatment. It will take several treatments. My wife has the same as you, breast cancer, came after 3 years to hip and spine, she started 45 days ago RSO, high levels of thc, everything has become better, she is having the best quality of life that you can imagine, and the most important is that the pain in the cancer areas is gone, the only thing it bother her is her joints, if another member of my family gets cancer, I will treat them straight with RSO.

    My mother has stage 4 cancer. We live in California. I finally went and got some cannibus oil, which seemed to help her out a lot. Gave her a lot of energy. But her new chemo medication is killing her. Can you please tell me where you were able to get RSO? I really want my mother to try that out and see if it helps out at all.

    Thank you for letting me know Patricia! Do you know any specific stores that have them? She is doing ibrance now with a minimum dosis of RSO, and really help her with everything, pain, nausea, bowels movement, to sleep, I mean you can see the difference. Hi im in the uk my mum has the same breast cancer now gone to bones secondary hospital say they can do nothing where do you get the correct oilfrom please where im notgoing to get ripped off and can get shipped?

    Makes me soooooo Angry! I had no way home until my jeep was brought to me. I took off home and was back in less than two hours. Phenergan, Zofran, Ativan, Marinol, Zyprexa, Periactin and Prilosec all on board at the same time and still dry heaving with a temp of Temp down to normal. Up walking around and ABC hit within 24 hours. My husband has stage 4 colon cancer and chemo was not bringing his CEA numbers down.

    He has been using Cannabis oil for almost a month and his numbers dropped 20 points! Frankel in CA was wonderful helping us with it. Fight no matter what! No one will understand what they are not themselves going through!! Have you ever heard of the Georgia Guide Stones? They plainly state that there should be no more than ,, human beings alive on this planet at any time.

    If you do the math; at least 7. Think about that the next time you take a prescribed pill. I really feel sorry for anyone who takes chemo. It destroyes any abillity that your body has to fight disease. It may put your cancer into remission, but it will in most cases come back and kill you in a few years. My prayers go out to you.

    I just need something for my crushed spine: I have read the Sour Tsunami works like a miracle—but so far cannot find any. Any suggestions out there? Hey Dan Dan, I have the same issue. I have had good results from other high cbd strains, such as MediHaze and Candy Land. I believe in him and his oil. I really wish I had heard about him earlier as I lost my fiance to cancer in I was in the Medical field for over 35 yrs and the one thing I have noticed is how the Medical society has gone from Health Care to Business.

    Add the poison the Monsanto and Big Ag have put in our foods, only to have Big Pharma follow behind with their meds, and the answer should be clear. Something God put on this earth. Keep up the good work, Rick! While in Canada he grew the plants, made the oil and gave the oil to sick people free of charge. That wss what i was talking about. What an irresponsible and asinine thing to recommend. Food-grade ethanol should be used. Even CO2 is better than iso. But in terms of fighting cancer, cannabis extracts absolutely have that effect.

    You can download my book on the subject at http: That study shows the half-life is 1 hour and peak plasma blood levels are between 0. So a person would need to take grams at hour zero followed by grams every hour after in order to have a modest effect on the growth rate their cancer assuming it works.

    A number of factors account for the low oral bioavailability including variable absorption per person, degradation in the stomach, significant first-pass metabolism to active and inactive metabolites in the liver and so on https: That is some good science there but is inherently flawed because the dosing does not translate to humans. The overall concepts appear to however. Clearly humans do not need to take such massive quantities or they would not be seeing anticancer results in the 50mg — mg per day range.

    When cannabinoids are used in humans, in the context of the fully-functioning endocannabinoid system, it works entirely differently than in a petri dish. If you are truly interested in seeing this work in humans, you can read my book linked to above. If you do not wish to see the actual human evidence, there is nothing I can do.

    If you want to use grain alcohol be my guest. Send tge herb to me and i will gey the. Vaped or dabbed ISO hash oil for quite a while. Also with iso how do you know there is no residual solvent? And if you get the residual solvent to absolute 0 you lose valuable medicinal terpenes. With food-grade alcohol you can leave a few hundred parts per million with no issues, which enables you to not overheat and preserve terpenes.

    For smoking you would want to get 0ppm. But what if you mess up or the lab is wrong and there is some residual solvent? Hell, you could even use vodka as a solvent. What is the difference between RSO and regular oil, if any? Where is the benefit in this particular method? This article, while informative, fails to cover some salient points. I had great results topically on a squamous cell carcinoma on my arm, but my sister, who has lung cancer, would get so dizzy with it, that she fell several times, and stopped taking it.

    She got very dizzy every time thruout she was taking it. Quacks like Rick Simpson do those who think that cannabinoids have promise in treating cancer no favors.

    Marc Emery has also called him out in the past: I never could see any so-called sworn affidavits. I could never interview any patients. I could never get the formula used, or the strain, or anything specific whatsoever.

    That is why no journalist has been able to write about Simpson, he is unverifiable, in his claims, his patients, his documentation, everything, really. No solid paperwork either. Secondly, its cowardice to stay in Europe when Simpson should, to me, obviously come back and prove his claims in court.

    Putting Simpson in jail for cultivation still seems very unlikely, especially since Bill C is not yet law. There is a great potential for a medical necessity defence. I find Simpson a bit of an odd fellow. Wow, your comment is one of the most ignorant things I have read in a long time.

    Honestly, I dont even know where to start with the misinformation in your post. First, Rick was in court and tried to brnig patients in. They did not allow it. Are you unaware of that? So your statement about him coming back and proving his claim in court just makes no sense whatsoever. Either you are truly an idiot or really reaching here to find something negative with Rick.

    Also, why would he want to return to Canada if there is no freedom there. Once again, stupid statement just trying to make Rick look bad. I dont know who Marc Emery is, but he sounds like a shill to me and so do you. My husband has been using cannibas oil and his colon cancer diagnosis is improving — his tumor marker number has dropped 20 points and his liver function has vastly improved.

    Science doesnt want to back up a study if there is a government that says a plant is illegal and no studies are allowed into it. There are a number of U. The company hopes it will be approved this year and placed into Schedule 4. Great, just what we needed, a company that conducts trials with supposed natural plant ingredients. Keep your messed up synthetical junk to yourself, the people dont want it anymore.

    MJ cant be controlled by big pharma, and if it would be, ppl will just grow their own for the sake of taking care of their health. I think by now, it is clear that you, James Peters, works for big pharma, since you are sooooooo interested in MJ but keep throwing us names of pharma companies and who is conducting what tests. Government is part of big corporations, big corporations include pharma companies, so literely i dont give a rats ass if pharma companies are conducting tests, because we end up with the same old junk as always: Marinol was designed to fail.

    Synthesize 1 out of 84 cannabinoids and release it for testing. Then when it failed said. I dry sift the trichomes of 1. Currently i am experimenting with micro doses milligrams a day. I have Crohns disease. Before MMJ I used to have flares a week, and could barely leave my home. Gout or arthritis pain in my joints. Joints red and inflammed easily running a fever of F in the affected joints.

    What it did was suppress my autoimmune response so my gut health no longer bounces between two extremes. There are a few peer-reviewed journals that are devoted to publishing case reports alone, and they are all open access.

    I think the fact no others have been published in all these years speaks volumes. Even if there had been then they would come close to the bottom in terms of hierarchy of evidence.

    A quick search of PubMed brings back many hundreds of studies. Yet the results are too modest for most pharma companies to be funding human clinical trials to test them. The case study is the more grassroots approach, and every time some person uses cannabis to get well, that is a case study. I bet James does case studies without even knowing it.

    Only one case study has been published https: Your so called case study is blown to smithereens as there is over a thousand different strains and methods to extract.

    Did you read it? A brave, brave, noble man. Like a modern day Christian Alchemist…a Nobleman Rosicrucian…in its original and finest sense of meaning. The science of Cannabinoids is rapidly moving forward. It appears to be just as effective on Cancer, pain and many others conditions no one relates to RSO. Plus when made from a high CBD less than. It has changed my life and as I take it daily I am convinced I will never get Cancer.

    I only use those which are CO2 extracted with hemp seed oil as the emulsifier agent. Thousands of people claim they have killed their Cancer with this legal oil. My son has stage 4 cancer , and doctors said he is done and nothing they can to save him , he manage to get this oil and is still here , doctors said they were not the ones keeping him alive.. I absolutely love the idea of using natural ingredients to heal the body.

    Can anything else but alcohol be used? Just seems so toxic. It is not potent in the way RSO is but also not extracted via extreme alcohol or dangerous solvent. The coconut infused with the cannabis makes it food worthy. In careful amounts it can go on say toast in the morning with breakfast and maybe a teaspoon straight of the spoon around lunch or later afternoon and again at dinner melted in rice or something.

    Closer to all natural than harsh solvents. In this way I can continue to utilize cannabis as a food. I am about to harvest my outdoor plant and will turn some of it into RSO for topical use of basal and squamous cell carcinoma. So depending on strength you seek, would depend on extract used. I do make a tincture though with less strength alcohol to carry with me when traveling. Easier than taking oil when I can drop the tincture into my coffee or other beverage.

    I also do not utilize either alone as medicine but in addition to diet and herb changes that I will do for life. It is amazing to me how much it helps aches and pain in general as well as smoothes big polar flares. Also a nice cup of hot tea with fan leaves or trimmings would be a lovely natural way to consume.

    I live New Zealand. My Sister was diagnosed of melanoma cancer and she have done many chemotherapy and it did not work, the cancer keeps returning. A friend of the family told us about cannabis oil and its curing ability in treatment of any type of cancer. I purchased the cannabis oil by emailing cannabisoil gmail. After using the oil for the duration of time given, my sister was totally free from cancer but i was advised she takes the oil continuously to maintain good health and reduce high blood pressure.

    I am so happy now that my sister is free from cancer and if you are suffering from cancer and the family is happy again. Cannabis oil is a natural treatment for cancer without any side effect. Taking a closer look at this recipe, I must admit the use of such solvents makes me a bit nervous. Is it possible to just steep the buds and leaves as a tea like when making sun brewed iced tea? I assume perhaps this method produces a higher amount of THC released from the plant when drawn out by the isopropyl which perhaps might be more appropriate for fighting back cancer or any precursors for those at high risk I suppose.

    This isopropyl alcohol, I assume is the same isopropyl alcohol used most commonly as an antiseptic as is found in alcohol swabs or what used to get used to clean wounds, until further research discovered it also acted as an irritant.

    But still, how much worse than can it be than chemo? I was going to say it surely cannot be anywise than using chemo alone. I suppose just steeping the buds in hot water and drinking it as a tea is out of the question or what?

    I live in Queensland, Australia. They have legalized it for Ltd use. But to get it is almost impossible due to LONG paperwork. We have been using cannabis oil with a 1: The medication is working with super proof. We recommend you visit AnnCannMed for your health prescriptions and medical purchases and feel support talking to licensed physicians.

    Your advise was very helpful. I did just as you suggested and have received my medicines from them without any headaches. You were right, they are quite professional. A close relative was on her last leg with her stage 4 cancer. She had collapsed due to a mass on her neck that had restricted her airway. This was her fighting chance and today her scans are clear. Her doctor stated that their is no cure for her cancer….

    You see it online or read an article here and there about these incredible stories and you choose to believe them or not, but I witnessed this with my own eyes. And let me tell you, it works. I never received anything from Rick Simpson. This guy should be ashamed of himself and should be in jail for scamming people who have cancer! I got some of this for my brother who was recently diagnosed with adenocarcinoma.

    My question is will it show a positive THC result in a mouth swab test. Thanks for any info. I ordered from this company which ships globally very discretely, high quality fresh rick Simpson oil. We ordered it for my father in law who has liver cancer. Comes in the mail this week. It comes in a suppository, we ordered a 90 day supply. So happy to be almost completely pain free everyday. Thanks to them I can treat my disease without taking basically speed.

    My life, appetite, and overall happiness has improved a lot: My mother in law is suffering from Parkinson Disease and I feel that she is being given too much dopamine causing hallucinations daily. Can anyone recommend anything to help her tremors to avoid too much medication? Going to be trying it for the first time tonight. I deal with a LOT of pain and have been mostly horizontal for months now. I have procedures set up to try to improve by low back pain and then it will leave me with just my fibro pain and whatever further deterioration occurs in my spine.

    Cannabis is the most important medicine in the world and its total range of benefits are not known. What is know is that big pharma hates it because almost anyone can grow it almost anywhere and it does no harm. As the Earth Protector founder, based in Minnesota, I know this is true from decades of use and study.

    Has it helped anyone or does anyone have any advice or suggestions? I do live in a state where it is legal. I have a personal story to tell about the use of Cannabis. A goody 2 shoes. I was finally diagnosed after months of misdiagnoses , in mid September with metastatic colon cancer…Stage 4…inoperable lesions all over my liver, multiple tumors through my body cavity, in the soaz muscle, etc: I had surgery where 2 feet of colon was removed along with my right ovary, appendix and all the tumors except those in the liver.

    After lots of research, we decided to do the Rick Simpson Oil treatment…at the same time as chemo. And I had to buy a whole pound of high quality bud…I started speaking the language of drug dealers! I had to boil it down I used Naptha and guess on the dosing.

    How big is a short grain of rice? Unscientific but no other way!!! I was scheduled for 12 infusions. Chemo hit me hard. I got every side effect listed for each of the poisons in my infusions. But I managed, despite staying on the sofa, uncomfortably high, for 3 months, I managed to kick this. I slept like a baby. But I got other nasty side effects from the chemo.

    So the Dr stopped chemo after 6 infusions because of the severe side effects…he said he nearly killed me. I got a clear PET scan.

    No sign of disease. No sign of cancer. Tumors in liver had shrunk and are not active. Of course, the Dr insists it will come back. More good news, Feb 15, My tumor markers were in September, in January, and now are Incidentally, I had a droopy eye that tightened up. And it appears that it also cured my hyperthyroidism …waiting on bloodwork now.

    People are calling me…neighbors, friends, strangers! A man with terminal kidney cancer metastasized all over…given weeks to live… is improving and Dr is stunned, saying maybe more weeks. Another man, 82, Stage 4 kidney cancer was sent home from the hospital on a Saturday morning 2 weeks ago…to die. He started his RSO on Saturday night. Doc was shocked when he showed up for radiation Monday morning. His kidneys had shut down, legs and feet so swollen they looked about to burst, but then he started peeing again.

    That week he improved and got 16 more treatments. For a more thorough decarbox y-. Besides cannabinoids, the cannabis plant contai ns a. Our te sts were i ntended to be t-. Figure 1A shows the cannabinoid profile of the dec a r-. Further conversion of THC into.

    Fig ures 1B and 1C show the terpene p rofile acquired in. After the more intense. As may be expected, the less volatile sesquite r-.

    However, most of them were lost in the. These data indicate t hat significant decarbo xylation of. However, under these conditions all major. Although milder d ecarboxylation using a boiling. For this reason, all. Analysis of the extracts: Analysis by HPLC to reveal the ratio between acidic. Results are shown in Figure 2A. Most extracts co n-. This is re markable because. P erhaps added chemicals e. Analysis of the extracts by GC indicated that t he major.

    This is in agreement with p revious. The extraction solvents showed co mparable efficiency. While this solvent gene r-. It is not known whether i these. Interestingly, t he use of petroleu m. The use of olive oil as extraction solvent was found to. This may be e x-. Treatment of the ethanolic extract with activated cha r-. For this reason, the use of charco al should not. Naphtha and petroleum ether are mixtures of various.

    All t he solvent co mp o-. Both naphtha and petro leum ether are co n-. Moreover, products sold as. For these reasons, the naphtha and petro leum. As may be e x-. In t he naphtha extract, based on GC.

    Reconfirmation using an actual patient sample. In o rder to confirm our experimental resul ts, we also. The patient was a The anal ytical results data not shown. Concentrated cannabis extracts, also known as Can n a-. Recognizing the need for. Based on the results of our preheating experiments,. Cannabis oils often claim the holis tic nature of cann a-. Retai ning the full spectrum of terpenes present.

    When comparing five methods of Cannabis oil prepar a-. Specifically t he prepar a-. Accord ing to the Simpson we b-. In other words, the curative pro p-. Che mical anal ysis of our laboratory sa m-. The potential harmful ef fects of these so lvent. It should be noted that as a result of sample viscosity,.

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    LR was funded for t his research by the Puglia Italy. AH is the head o f Research and Development at Be d-. Cannabinoid-associated ce ll death mechanisms in.

    Cancer ; 12 6: Cannabis as an antiemetic and app e-. Jefferson, NC, ; pp Recent clinical exp e-. Noyes R, Baram DA. Tetrahydrocannabinol for tremor in. Neurol ; 13 6: Cannabis in move ment disorders. Do cannabinoids cure cancer? Pharmacokinetics and pharm a-. Rick Simpson official website: Hazekamp A, Fi schedick JT.

    Cannabis - fro m. T owards a better definition. Drug T esting and Analysis. WHO International Agency for. IARC monographs on the. These naturally occurring compounds include deltatetrahydrocannabinolic acid, and cannabichromenic acid, which are converted into THC and CBD [12]. Higher temperatures increase the concentration of THC. Terpenes are also present in cannabis; they are responsible for the cannabis odor and might result in cannabinoid-effect augmentation.

    High temperatures decrease terpene concentrations [12]. Vaping leads to a release of a higher concentrations of active ingredients and less carcinogens, in comparison to smoking, since the temperatures utilized by vaping are lower [9].

    Cannabis oil is the most common source utilized in vaping and relies on several different solvents, such as naptha, petroleum ether, or olive oil for extraction. Some solvents are toxic and even small concentrations are not safe [12]. Vaping instruments are available in the market with great variations, ranging from big devices, to small pen-like gadgets.

    The most popular product currently is CBD oil, but for example cannabigerol CBG -rich oil has been spotted as well [2], and others will very likely follow soon. The THC-rich type of cannabis oil has already been known for some years, and is generally known under the name "Simpson oil" [3]. Terpenes may or may not be present in these products, depending on the preparation method used [4]. If any of these contaminants were present in hemp used for CBD extraction, they would likely end up in a concen- trated form in the final oil.

    One contaminant specifically relevant to cannabis CBD or THC oils is the residual presence of toxic solvents used during the extraction pro- cedure [3]. In just a few years, cannabidiol CBD has become immensely popular around the world.

    After initially being discovered as an effective self-medication for Dravet syndrome in children, CBD is now sold and used to treat a wide range of medical conditions and lifestyle diseases. The cannabinoid CBD, a non-psychoactive isomer of the more infamous tetrahydrocannabinol THC , is available in a growing number of administration modes, but the most commonly known is CBD oil.

    There are currently dozens, if not hundreds, of producers and sellers of CBD oils active in the market, and their number is increasing rapidly. Those involved vary from individuals who prepare oils on a small scale for family and Facebook friends to compounding pharmacies, pharmaceutical companies, and licensed cannabis producers.

    The central question is whether CBD is simply a food supplement, an investigational new medicine, or even a narcotic. This overview paper looks into the known risks and issues related to the composition of CBD products, and makes recommendations for better regulatory control based on accurate labeling and more scientifically supported health claims.

    The intention of this paper is to create a better understanding of the benefits versus the risks of the current way CBD products are produced, used, and advertised. Although the preparation of cannabis oil is relatively simple Romano and Hazekamp, , the quali- quantitative composition of the final products is poorly characterized, particularly considering that variations in temperature and time of extraction may impact on the final concentration of cannabinoids Citti et al.

    Magistral preparations of therapeutic cannabis are extracted from standardized products imported from Holland or from the Florence Military Pharmaceutical Chemical Works, but extraction protocols differ among galenic laboratories. No significant inter-laboratory variability emerged for Bedrocan and Bedrolite. Quantitative variability of cannabinoids in magistral preparations might impact on the efficacy and safety of therapeutic cannabis.

    Various strategies have been pursued to extract and deliver the pharmacological agents from Cannabis. The use of chemical solvents such as petroleum ether, ethanol or naptha are likely to leave unwanted residues, whereas extractants such as olive or coconut oil provide a more organic alternative [8]. Cannabis, from Plant to Pill. The therapeutic application of Cannabis is attracting substantial public and clinical interest.

    The effective delivery of such a complex multicomponent pharmaceutical relies upon the stable genetic background and standardised growth of the plant material, particularly if the raw botanical product in the form of the dried pistillate inflorescence flos is the source. Following supercritical CO2 extraction of the inflorescence and possibly bracts , the secondary metabolites can be blended to provide a specific ratio of major cannabinoids THC: CBD or individual cannabinoids can be isolated, purified and supplied as the pharmaceutical.

    Intensive breeding strategies will provide novel cultivars of Cannabis possessing elevated levels of specific cannabinoids or other secondary metabolites. Each of these extract forms have higher average THC concen- trations than do traditional forms of cannabis. Additionally, there are increased risks with the novice production of concentrates e. Leveraging user perspectives for insight into cannabis concentrates.

    The US has seen an increase in the popularity of highly concentrated forms of cannabis hereafter concentrates and too little is known about the potential risks associated with their use. The present study aims to better understand the patterns and outcomes of concentrates use through the perspectives of young adult users. They were queried on concentrates use patterns e.

    A total of Those who used for medical purposes or lived in states where use is legal were more likely to use concentrates frequently. Continued research on concentrates use in the US is needed. Research-informed policies that foster safe and responsible use of concentrates are necessary to protect users, especially those who use concentrates frequently, from potential negative side effects. Ethanol extracts have also been evaluated, considering the higher solubility of the active principles in this solvent than in water [11].

    The use of plant oil as an extraction solvent can be a safe alternative [16]. Recently, an increasing number of pharmacists had to supply medicinal products based on Cannabis sativa L. Cannabaceae , prescribed by physicians to individual patients. Cannabis olive oil preparation is the first choice as a concentrated extract of cannabinoids, even though standardized operative conditions for obtaining it are still not available.

    In this work, the impact of temperature and extraction time on the concentration of active principles was studied to harmonize the different compounding methods, optimize the extraction process, and reduce the variability among preparations. Moreover, starting from the cannabis inflorescence, the effect of temperature on tetrahydrocannabinolic acid decarboxylation was evaluated.

    Pharmacokinetics and tolerability of oral cannabis preparations in patients with medication overuse headache MOH —a pilot study. The recent release of a medical cannabis strain has given a new impulse for the study of cannabis in Italy.

    The National Health Service advises to consume medical cannabis by vaporizing, in decoction or oil form. This is the first study that explores the pharmacokinetics and tolerability of a single oral dose of cannabis as decoction ml or in olive oil 1 ml , as a first step to improve the prescriptive recommendations.

    This is a single-center, open-label, two-period crossover study designed to assess the pharmacokinetics and tolerability of oral cannabis administered to 13 patients with medication overuse headache MOH. Blood pressure, heart rate, and a short list of symptoms by numerical rating scale NRS were assessed.

    Decoctions of cannabis showed high variability in cannabinoids content, compared to cannabis oil. No serious adverse events were reported. Cannabis decoction and cannabis oil showed different pharmacokinetic properties, as well as distinct consequences on patients.

    This study was performed in a limited number of patients; future studies should be performed to investigate the clinical efficacy in larger populations.

    An overview of galenic preparation methods for medicinal cannabis. Cannabidiol CBD -based oil preparations are becoming extremely popular, as CBD has been shown to have beneficial effects on human health.

    CBD-based oil preparations are not unambiguously regulated under the European legislation, as CBD is not considered as a controlled substance. This means that companies can produce and distribute CBD products derived from non-psychoactive hemp varieties, providing an easy access to this extremely advantageous cannabinoid.

    This leaves consumers with no legal quality guarantees. The objective of this project was to assess the quality of 14 CBD oils commercially available in European countries. Nine out of the 14 samples studied had concentrations that differed notably from the declared amount, while the remaining five preserved CBD within optimal limits.

    Our results highlighted a wide variability in cannabinoids profile that justifies the need for strict and standardized regulations. In addition, the terpenes fingerprint may serve as an indicator of the quality of hemp varieties, while the lipid oxidation products profile could contribute in evaluation of the stability of the oil used as milieu for CBD rich extracts. Contemporary Routes of Cannabis Consumption:

    FAQ about RSO

    RSO is an acronym for Rick Simpson Oil and is one of the many forms of So in short, cannabis RSO can feature THC or CBD as its majority. Simpson had had success in treating other ailments in the past, and decided to try treating his skin cancer with high-THC cannabis oil. Simpson. If you're interested in learning how to make Rick Simpson Oil on are usually found in a 1 milliliter syringe, but the contents of each is very different. on the skin, anal suppository, vaginal suppository and the list goes on.

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    tor111

    RSO is an acronym for Rick Simpson Oil and is one of the many forms of So in short, cannabis RSO can feature THC or CBD as its majority.

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